The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 1987
Filed:
Oct. 26, 1984
Applicant:
Inventors:
Karl-Heinz Schmidt, Wankheim, DE;
Wolfgang Feller, Melsungen, DE;
Assignee:
Intermedicat GmbH, Emmenbrucke, CH;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07G / ; C07C / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
525 541 ; 530350 ; 530402 ; 530813 ; 530816 ; 514-2 ; 514-6 ; 514-7 ; 514-8 ; 514 54 ; 514 59 ; 514 60 ;
Abstract
The invention relates to an allosterically active conjugate composition comprising one or more hemoglobin tetramers and one or more adducts of a physiologically safe macromolecular agent covalently linked to one or more ligands, such that the adduct is bound to the allosteric binding site of the hemoglobin in a reversible, non-covalent manner; the invention also relates to methods for producing such conjugate compositions; and to blood substitutes or plasma extenders containing such conjugates.