The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 1987
Filed:
Nov. 18, 1985
Elmar Sturm, Aesch, CH;
Peter Maienfisch, Aesch, CH;
Ciba-Geigy Corporation, Ardsley, NY (US);
Abstract
The present invention relates to milbemycin derivatives of the formula I ##STR1## wherein X is hydrogen or .beta.-halogen, R is methyl, ethyl, isopropyl or sec-butyl and Az is a 5 membered heterocyclic aromatic ring which contains 2-4 nitrogen atoms and is attached in the 1-position and which is unsubstituted or substituted by one or two C.sub.1 -C.sub.6 alkyl groups. These compounds, and the acid addition salts and metal complexes thereof, are effective pesticides for controlling endo-and ectoparasites, especially for controlling neamatodes which are parasites of animals. The may be obtained by appropriate esterification in 5-position of milbemycin derivatives. The selective .beta.-halogenation of 14,15-epoxymilbemycin derivatives can be effected via the intermediate .DELTA..sup.13,14 -15-hydroxymilbemycins with appropriate halogenating agents.