The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 22, 1987

Filed:

Dec. 19, 1984
Applicant:
Inventors:

Naohito Ohashi, Newton, MA (US);

Shoji Nagata, Takarazuka, JP;

Masashi Nakatsuka, Osaka, JP;

Kikuo Ishizumi, Toyonaka, JP;

Junki Katsube, Toyonaka, JP;

Shunji Aono, Toyonaka, JP;

Teruo Sakurama, Toyonaka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514412 ; 514414 ; 514415 ; 514416 ; 514422 ; 514423 ; 540520 ; 544162 ; 544391 ; 546146 ; 546226 ; 546309 ; 548251 ; 548452 ; 548455 ; 548465 ; 548467 ; 548482 ; 548517 ; 548518 ; 548525 ; 548526 ; 548527 ; 548533 ; 548536 ; 548540 ; 560 27 ; 560 29 ; 560 39 ; 562448 ; 564165 ;
Abstract

Novel phenylserine derivatives of the formula: ##STR1## and pharmaceutically acceptable acid addition salts thereof, pharmaceutical compositions, and a process for preparing the compounds are disclosed. The phenylserine derivatives and pharmaceutically acceptable acid addition salts are capable of inhibiting the biosynthesis of leucotrienes and/or antagonistic activity against SRS-A and hence are useful for prophylaxis and treatment of various allergic diseases (e.g. bronchial asthma, allergic nasitis, urticaria), ischemic heart diseases, ischemic encephalopathy, inflammation, or the like.


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