The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 11, 1987

Filed:

Aug. 12, 1985
Applicant:
Inventors:

Michael N Chang, Westfield, NJ (US);

Norman P Jensen, Princeton, NJ (US);

Milton L Hammond, Somerville, NJ (US);

Robert A Zambias, Springfield, NJ (US);

John McDonald, Indianapolis, IN (US);

Kathleen M Rupprecht, Cranford, NJ (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; A61K / ;
U.S. Cl.
CPC ...
514520 ; 514522 ; 514525 ; 514533 ; 514544 ; 514546 ; 514568 ; 514685 ; 514708 ; 514710 ; 514701 ; 514713 ; 514720 ; 514733 ; 514456 ; 514469 ; 558413 ; 558414 ; 558415 ; 558416 ; 558423 ; 560 11 ; 560 18 ; 560 53 ; 560 59 ; 560 65 ; 560 66 ; 560 67 ; 560138 ; 560141 ; 562429 ; 562432 ; 562463 ; 562469 ; 562473 ; 562475 ; 568 31 ; 568 33 ; 568 37 ; 568 43 ; 568 47 ; 568 49 ; 568 52 ; 568337 ; 568442 ; 568637 ; 568638 ; 568645 ; 568646 ; 568744 ; 568745 ; 549405 ; 549408 ; 549462 ;
Abstract

Substituted cinnamyl-2,3-dihydrobenzofurans and analogs were prepared from the nucleophlic substitution of a cinnamylhalide with a 2,3-dihydrobenzofuran anion or an analog thereof. These compounds were found to be potent topical anti-inflammatory agents.


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