The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 1987
Filed:
Jan. 22, 1985
Applicant:
Inventors:
Ivars Y Kalvinsh, Rizhsky, SU;
Elena B Astapenok, Riga, SU;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514183 ;
Abstract
The pharmaceutical composition possessing antitumor activity against tumors susceptible to 2-carbamoylaziridine which consists of a therapeutically efficaceous quantity of 1-H-2-aziridinecarbonic acid derivative having the formula ##STR1## where R is NH.sub.2 and a pharmaceutically suitable solvent or filler. The pharmaceutical composition possesses a high activity against tumors susceptible to 2-carbamoylaziridine, a wide spectrum of antitumor effect and low toxicity (LD.sub.50 within the range of 3,000 and 3,500 mg/kg. The invention is also a method for treating malignant tumors susceptible to 2-carbamoxylaziridine by administration of 2-carbamoyl-aziridine.