The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 21, 1987
Filed:
Jun. 06, 1985
Applicant:
Inventors:
Rainer Obermeier, Hattersheim am Main, DE;
Ingeborg Salomon, Wollstadt, DE;
Jurgen Ludwig, Brachttal, DE;
Assignee:
Hoechst Aktiengesellschaft, , DE;
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; A61K / ; C12P / ;
U.S. Cl.
CPC ...
530351 ; 424 85 ; 435 68 ;
Abstract
The invention relates to a process for the isolation and purification of .alpha.-interferons generated by plasmids from bacterial cultures which have been modified by genetic engineering, and of .alpha.-interferons from culture supernatants of induced mammalian cells, which comprises partition of appropriate crude substances containing interferon between an aqueous urea solution, which contains a surfactant, and a mixture of n-butanol and glacial acetic acid which contains water, and isolation of the purified .alpha.-interferons from the upper phase.