The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 1987
Filed:
Mar. 01, 1985
Lee B Eppstein, New Brunswick, NJ (US);
Robert D Mohler, Bridgewater, NJ (US);
Shaul Reuveny, Highland Park, NJ (US);
New Brunswick Scientific Company, Inc., Edison, NJ (US);
Abstract
A method and an apparatus for controlling the concentration of oxygen and pH of a medium during a bioreaction process in a vessel. The method and apparatus are particularly adapted to a fermentation process. A dissolved oxygen sensor generates a signal corresponding to the pH of the medium and a dissolved oxygen sensor generates a signal corresponding to the dissolved oxygen in the medium. A valve mechanism selectively applies air, N.sub.2, O.sub.2 and CO.sub.2 to the medium. A controller produces a control signal for controlling the operation of the valve means so that a substantially fixed volume of gas consisting of one or more of air, CO.sub.2, N.sub.2 and O.sub.2 are added to the fermenting medium during a period of time. The controller determines in response to the dissolved oxygen and pH signals, the amount of CO.sub.2, O.sub.2 and/or N.sub.2 required to effect dissolved oxygen and pH correction. The controller further adjusts these determined values to compensate for the displacement of the CO.sub.2 added. As a result, the effect of the CO.sub.2 correction on the dissolved oxygen is substantially minimized.