The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 1987

Filed:

Sep. 02, 1986
Applicant:
Inventors:

John J Baldwin, Gwynedd Valley, PA (US);

Wasyl Halczenko, Hatfield, PA (US);

George Hartman, Lansdale, PA (US);

Steven M Pitzenberger, Lansdale, PA (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07C / ;
U.S. Cl.
CPC ...
514539 ; 514400 ; 514419 ; 514423 ; 514533 ; 514547 ; 548342 ; 548496 ; 548532 ; 548535 ; 560 16 ; 560 39 ; 560 40 ; 560153 ; 560169 ; 560170 ; 562426 ; 562444 ; 562445 ; 562557 ; 562559 ; 562564 ; 562567 ;
Abstract

Prodrugs of 3-hydroxy-3-methylglutarylcoenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formula (I): ##STR1## the amido ester moiety of which is in the L-configuration, and pharmaceutically acceptable salts thereof are disclosed.


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