The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 1987

Filed:

Jul. 26, 1985
Applicant:
Inventors:

Charles F Jewell, Jr, Atlanta, GA (US);

James R Wareing, Randolph, NJ (US);

Assignee:

Sandoz Pharmaceuticals Corp., E. Hanover, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07F / ; C07F / ; C07C / ;
U.S. Cl.
CPC ...
548491 ; 260408 ; 2604105 ; 2604 / ; 548406 ; 549214 ; 549292 ; 549407 ; 549417 ; 549209 ; 556437 ; 560 56 ; 560 59 ; 560 60 ; 562466 ;
Abstract

7-Substituted lower alkyl hept-6-enoates and 4-hydroxytetrahydropyran-2-ones bearing 6-olefinic substituents (e.g.,) ethyl erythro-3,5-dihydroxy-7-phenyl-hept-6-enoates are prepared by a multi-step process. The process involves 3-protected-lower alkyl 3,5-dihydroxy-hept-6-enoates, which are obtained by cleaving corresponding 6.alpha.-vinyl-4.beta.-protected hydroxy-tetrahydro 2H-pyran-2-ones. The final products are useful as anti hypercholesteremic agents.


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