The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 1987
Filed:
Feb. 24, 1984
Marc Julia, Paris, FR;
Therese Cuvigny, Paris, FR;
Roussel Uclaf, Paris, FR;
Abstract
A novel process for the preparation of pent-4-enoic acids of the formula ##STR1## wherein X is selected from the group consisting of hydrogen, cyano and alkoxycarbonyl of 2 to 5 carbon atoms and Y is selected from the group consisting of hydrogen, cyano, alkoxycarbonyl 2 to 5 carbon atoms, acyl of an organic carboxylic acid of 2 to 7 carbon atoms, alkylsulfonyl of 1 to 4 carbon atoms and arylsulfonyl of 6 to 7 carbon atoms with the proviso that X and Y are not both hydrogen comprising reacting a compound of the formula ##STR2## wherein R is selected from the group consisting of acyloxy of an organic carboxylic acid of 1 to 7 carbon atoms, alkylsulfonyl of 1 to 4 carbon atoms and arylsulfonyl of 6 to 7 carbon atoms with an anion derivative of a compound of the formula ##STR3## wherein X.sub.1 and Y.sub.1 have the above definition for X and Y, respectively, except hydrogen in the presence of a palladium compound or nickel (o) complex and optionally a catalytic quantity of a ligand to obtain a compound of the formula ##STR4## wherein X.sub.1 and Y.sub.1 have the above definition and optionally subjecting the latter to a decarbalkoxylation when X.sub.1 or Y.sub.1 is alkoxycarbonyl or to a reduction when X.sub.1 is arylsulfonyl to obtain the corresponding compound of formula I.