The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 1987

Filed:

Mar. 27, 1986
Applicant:
Inventors:

Donald S Karanewsky, East Windsor, NJ (US);

Tamara Dejneka, Skillman, NJ (US);

Assignee:

E. R. Squibb & Sons, Inc., Princeton, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07F / ; C07F / ;
U.S. Cl.
CPC ...
514 63 ; 514 79 ; 514 80 ; 514 89 ; 514 92 ; 514 94 ; 514 95 ; 514 99 ; 514119 ; 544229 ; 544337 ; 546 14 ; 546 22 ; 546 23 ; 548110 ; 548112 ; 548119 ; 548406 ; 548413 ; 548414 ; 548953 ; 549-4 ; 549-6 ; 549214 ; 549218 ; 556 19 ; 558174 ;
Abstract

Compounds of the formula ##STR1## wherein X is various amino or imino acids and esters are disclosed. These compounds are useful as anti-hypertensive agents due to their angiotensin converting enzyme inhibition activity and depending upon the definition of X may also be useful as analgesics due to their enkephalinase inhibition activity.


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