The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 1987
Filed:
Sep. 14, 1982
Jiri Krepelka, Prague, CS;
Iva Vancurova, Prague, CS;
Karel Rezabek, Prague, CS;
Milan Melka, Hradec Kralove, CS;
Vojtech Pujman, Prague, CS;
Stanislava Pokorna, Prague, CS;
Ruzena Reichlova, Prague, CS;
Slavjanka Cernochova, Prague, CS;
SPOFA, spojene podniky pro zdravotnickou vyrobu, Prague, CS;
Abstract
Basic ethers of 7-oxo-7H-benzo(c) fluorene have been shown to evidence a pronounced antineoplastic and immunosuppressive effect in mammals suffering from leukemia. The technique for preparing the described ethers and the addition salts thereof with pharmaceutically acceptable organic and inorganic acids involves the aminoalkylation of 5-hydroxy-7-oxo-7H-benzo(c) fluorene and its corresponding nuclear substituted derivatives on the hydroxylic oxygen atom.