The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 1987
Filed:
Oct. 10, 1984
Applicant:
Inventors:
Robert A Nicolotti, Furguson, MO (US);
Richard T Dean, Chesterfield, MO (US);
Assignee:
Mallinckrodt, Inc., St. Louis, MO (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ; A61K / ; G01N / ;
U.S. Cl.
CPC ...
548546 ; 424-11 ; 424-9 ; 436512 ;
Abstract
Bifunctional coupling agent for joining radionuclide metal ions to biologically useful molecules, including antibody Fab' fragments are disclosed. The coupling agents contain a maleimide moiety and a paramagnetic or radionuclide chelating moiety. The maleimide can be used to selectively bind to free sulfhydryl groups, or amine groups.