The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 1987
Filed:
Oct. 25, 1984
Applicant:
Inventors:
Masakatsu Kaneko, Tokyo, JP;
Misako Kimura, Tokyo, JP;
Yoshinobu Murofushi, Tokyo, JP;
Mitsuo Yamazaki, Tokyo, JP;
Nobuyoshi Iwata, Tokyo, JP;
Fumio Nakagawa, Tokyo, JP;
Assignee:
Sankyo Company Limited, Tokyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ; C07D / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514262 ; 514266 ; 544264 ; 544265 ; 544276 ; 544277 ;
Abstract
Griseolic acid derivatives of formula (I): ##STR1## wherein A represents: ##STR2## have enzyme-inhibitory activity, especially against cAMP PDE and cGMP PDE. When formulated as compositions with appropriate carriers or diluents, they may be used for the treatment of a variety of organic disorders and show toxicities less than griseolic acid itself.