The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 30, 1986

Filed:

Apr. 13, 1983
Applicant:
Inventors:

Luigi Bernardi, Milan, IT;

Enzo Brambilla, Mariano Comense, IT;

Laura Chiodini, Busto Arsizio, IT;

Enrico di Salle, Milan, IT;

Daniela Ruggieri, Milan, IT;

Osvaldo Sapini, Gallarate, IT;

Aldemio Temperilli, Milan, IT;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; B07D / ; C07D / ;
U.S. Cl.
CPC ...
544329 ; 544310 ; 544317 ; 544318 ; 544319 ; 546 67 ; 546 69 ;
Abstract

There are provided ergoline derivatives of the formula: ##STR1## wherein R.sub.1 represents a hydrogen atom or a methyl group, R.sub.2 represents a hydrogen or halogen atom or a methyl group, R.sub.3 represents a hydrogen atom or a methoxy group, R.sub.4 represents a hydrocarbon group having from 1 to 4 carbon atoms; each of X and W independently represents a hydrogen atom, a methyl group, a chlorine atom or a methoxy group, and n is 0, 1 or 2. A method for their preparation is also provided. The compounds have strong antiprolactin activity.


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