The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 1986
Filed:
Jul. 12, 1985
Takeo Yoshioka, Ayase, JP;
Miharu Maeda, Yokohama, JP;
Rokuro Okamoto, Fujisawa, JP;
Yasutaka Shimauchi, Ninomiya, JP;
Tomoyuki Ishikura, Chigasaki, JP;
Tsutomu Sawa, Ayase, JP;
Tomio Takeuchi, Tokyo, JP;
Hamao Umezawa, Tokyo, JP;
Sanraku Incorporated, Tokyo, JP;
Abstract
Novel tylosin derivatives are represented by formula: ##STR1## wherein R represents a hydrogen atom, an acetyl group or a propionyl group; X represents a group --CO-- or --SO.sub.2 --; Y represents a fluorine atom, an acetyl group, a methanesulfonyl group, a methylthio group, a benzoyl group or a methoxy group bound to the benzyl group at the 2-position or 4-position; and Z represents a hydrogen atom or a D-mycinose residue: ##STR2## The tylosin derivatives which are antibiotics of macrolide type provide improved antibacterial activity and improved ability of absorption and excretion in vivo.