The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 1986
Filed:
May. 30, 1985
Charles L Fox, Jr, Fort Lauderdale, FL (US);
Shanta M Modak, River Edge, NJ (US);
The Trustees of Columbia University in the City of New York, New York, NY (US);
Abstract
An infection-resistant polymeric material, such as polytetrafluoroethylene, for use on or within a human or animal body, for example, in the form of a vascular graft, can be prepared by an improved method which comprises the following sequence of steps: (a) soaking a polymeric material with a solution of an antimicrobial agent, such as sodium sulfadiazine, oxacillin dissolved in an organic solvent therefor, such as an ethanol/chloroform mixture, (b) soaking the polymeric material with an organic solvent, such as ethanol, for a metal salt; and (c) resoaking the polymeric material with the solution of the antimicrobial agent dissolved in the organic solvent therefor. The polymeric material is dried after each soaking step. Preferably, in the intermediate soaking step (b) the organic solvent contains a metal salt, such as silver nitrate, dissolved therein, so as to form in situ the metal salt of the antimicrobial agent, such as silver sulfadiazine.