The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 1986
Filed:
Dec. 27, 1984
Stephen K Boyer, Far Hills, NJ (US);
Karl O Gelotte, Watchung, NJ (US);
Joseph Bach, Parsippany, NJ (US);
Ciba-Geigy Corporation, Ardsley, NY (US);
Abstract
Disclosed is a process for the preparation of a compound of the formula ##STR1## wherein Ar is 3- or 4-pyridyl or 3- or 4-pyridyl substituted by lower alkyl; R.sub.1 is hydrogen, halogen, trifluoromethyl, lower alkyl, hydroxy, acylated or etherified hydroxy, lower alkylthio; or two of R.sub.1 on adjacent carbon atoms represent alkylenedioxy; p is 1 or 2; R.sub.2 represents hydrogen or lower alkyl; E represents C.sub.1 -C.sub.11 alkylene, C.sub.1 -C.sub.6 alkylenephenylene, C.sub.1 -C.sub.6 alkylene-(thio or oxy)-lower alkylene, C.sub.1 -C.sub.6 alkylene-(thio or oxy)-phenylene, C.sub.1 -C.sub.6 alkylenephenylene-lower alkylene, phenylene-lower alkylene; or E represents a direct bond; and B represents carboxy, esterified carboxy or carbamoyl; which comprises deoxygenating the keto group in a compound of the formula ##STR2## wherein Ar, R.sub.1, R.sub.2, p, E and B have meaning as defined above.