The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 1986

Filed:

Feb. 10, 1983
Applicant:
Inventors:

Takashi Onishi, Kurashiki, JP;

Shigeaki Suzuki, Kurashiki, JP;

Fumio Mori, Kurashiki, JP;

Tetsuo Takigawa, Kurashiki, JP;

Yoshiji Fujita, Kurashiki, JP;

Masao Mizuno, Kurashiki, JP;

Takashi Nishida, Kurashiki, JP;

Assignee:

Kuraray Co., Ltd., Kurashiki, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07C / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
546294 ; 546268 ; 546340 ; 546344 ; 546283 ; 546284 ; 548146 ; 560106 ; 560254 ; 568 28 ; 568 32 ; 568 41 ; 568 55 ; 549 14 ; 549 22 ; 549 30 ; 549 39 ; 549374 ; 549375 ; 549416 ; 549453 ; 556427 ; 556428 ;
Abstract

Novel polyprenyl compounds have the general formula: ##STR1## represents a cis-isoprene unit, n is an integer of 11-19, Z.sup.1 is --CH.sub.2 OH or a functional precursor thereof, and either one of R.sup.1 and R.sup.2 is a hydrogen atom and the other is --S(O).sub.m R.sup.3 in which m is an integer of 0 (zero), 1 or 2 and R.sup.3 is a phenyl, naphthyl, pyridyl or thiazolinyl group or such group substituted with at least one lower alkyl and/or halogen substituent. The topic novel polyprenyl compounds can be synthesized from derivatives of the polyprenol which is obtainable from leaves of Ginkgo biloba or Cedrus deodara, among others, by extraction, if necessary followed by hydrolytic treatment. The novel polyprenyl compounds can be converted to mammalian dolichols or precursors thereof by reductive elimination of the --S(O).sub.m R.sup.3 group.


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