The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 1986

Filed:

Mar. 28, 1984
Applicant:
Inventors:

Ryuichi Iemura, Kawanishi, JP;

Tsuneo Kawashima, Osaka, JP;

Toshikazu Fukuda, Osaka, JP;

Keizo Ito, Osaka, JP;

Takashi Nose, Nara, JP;

Goro Tsukamoto, Toyonaka, JP;

Assignee:

Kanebo, Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514218 ; 544370 ; 2602456 ; 514253 ;
Abstract

Novel benzimidazole derivatives of the formula: ##STR1## wherein R.sup.1 is a lower alkyl group, a lower alkenyl group or a lower alkynyl group, R.sup.2 is hydrogen atom, a lower alkyl group or a lower hydroxyalkyl group, and n is 2 or 3, or a pharmaceutically acceptable acid addition salt thereof, which have potent antihistaminic activity with less toxicity and hence are useful as an antihistaminics, and a process for the preparation of the compounds, and a pharmaceutical composition useful as antihistaminics containing the compound as an essential active ingredient.


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