The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 1986

Filed:

Aug. 31, 1983
Applicant:
Inventors:

Richard J Zelinka, Lino Lakes, MN (US);

Keiichi Itakura, Arcadia, CA (US);

Carl W Sims, St. Paul, MN (US);

Bruce E Kaplan, Claremont, CA (US);

Assignee:

Systec Inc., Minneapolis, MN (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M / ; C12M / ; B67D / ; G05B / ;
U.S. Cl.
CPC ...
435287 ; 435289 ; 935 88 ; 436 89 ; 436 90 ; 222137 ; 525 541 ; 525 5411 ; 422 62 ; 422111 ; 422116 ;
Abstract

A microprocessor controlled, general purpose gene synthesizer for programmably synthesizing selected nucleotide sequences. Depending upon a programmed chemistry, metered volumes of selected bases and reagent/solvents are sequentially metered into the bottom of a reaction cell containing solid-supported nucleotides, where desired linkages are achieved in an agitated suspension. Self-refilling syringe metering and electrically initiated, pneumatically operated valving insures economical, non-contaminated synthesis. Preprogrammed, selectable chemistries and operator programmed sequences are operatively coupled under microprocessor control to ensure a general purpose synthesizer.


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