The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 1986
Filed:
Aug. 17, 1984
Applicant:
Inventor:
Philip R Page, Parede, PT;
Assignee:
Hovione Inter Ltd., , CH;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C / ;
U.S. Cl.
CPC ...
2603515 ; 2603511 ;
Abstract
A process for the preparation of .alpha.-6-deoxy-tetracyclines by the stereoselective heterogeneous hydrogenation of a 6-demethyl-6-deoxy-6-methylene-tetracycline or an acid addition salt thereof, in the presence of a tertiary phosphine, or the simultaneous dehalogenation and stereo-selective heterogeneous hydrogenation of an 11a-halo-6-demethyl-6-deoxy-6-methylene-tetracycline or an acid addition salt thereof, in the presence of a tertiary phosphine, characterized by the use of a rhodium salt catalysts, wherein the rhodium is bonded to a polysiloxane carrier, having the following formulae: