The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 24, 1986

Filed:

Jan. 23, 1984
Applicant:
Inventors:

Ernest D Nicolaides, Ann Arbor, MI (US);

Francis J Tinney, Ann Arbor, MI (US);

James S Kaltenbronn, Ann Arbor, MI (US);

Dana E DeJohn, Ann Arbor, MI (US);

Elizabeth A Lunney, Ann Arbor, MI (US);

W Howard Roark, Ann Arbor, MI (US);

Joseph T Repine, Ann Arbor, MI (US);

Assignee:

Warner-Lambert Company, Morris Plains, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514423 ; 530331 ; 514424 ; 514428 ; 544372 ; 544384 ; 548531 ; 548536 ; 548537 ; 548542 ; 548568 ; 548572 ; 560 25 ; 560 29 ; 560153 ; 560159 ; 560160 ; 560169 ; 530315 ;
Abstract

Modified oxytocin-vasopressin di- or tri-peptides wherein an amide group is replaced by a group selected from ##STR1## --CH.sub.2 NH--, --CH.sub.2 O--, --CH.sub.2 S--, --CH.sub.2 SO--, --CH.sub.2 SO.sub.2 --, --CH.sub.2 CH.sub.2 -- and --CH.dbd.CH-- are described as well as methods for their manufacture, pharmaceutical compositions and methods for treatment, especially of cognitive disorders, depression, morphine dependency and parkinsonism by adjunctive therapy.


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