The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 1986
Filed:
Jun. 04, 1984
Applicant:
Inventors:
Tesfaye Biftu, Westfield, NJ (US);
Thomas W Doebber, Scotch Plains, NJ (US);
San-Bao Hwang, Scotch Plains, NJ (US);
Thomas R Beattie, Scotch Plains, NJ (US);
Tsung-Ying Shen, Westfield, NJ (US);
Robert Stevenson, Lexington, MA (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514461 ; 549487 ; 549491 ; 514229 ; 549492 ; 549494 ; 514231 ; 549497 ; 549498 ; 514233 ; 549499 ; 514234 ; 549500 ; 514236 ; 549501 ; 549502 ; 514237 ; 549504 ; 514239 ; 514333 ; 514336 ; 514422 ; 514444 ; 514452 ; 514464 ; 514466 ; 514471 ; 514473 ; 544105 ; 546256 ; 546281 ; 546283 ; 548517 ; 548518 ; 549 60 ; 549362 ; 549429 ; 549435 ; 549472 ; 549473 ; 549475 ; 549483 ; 549485 ; 549486 ;
Abstract
Analogs of 2,5-Diaryl tetrahydrofurans which were substituted or unsubstituted at 3,4-positions were prepared. These compounds are found to have potent and specific PAF (Platelet Activating Factor) antagonistic activities and thereby useful in the treatment of various diseases or disorders mediated by the PAF, for example, inflammation, cardiovascular disorder, asthma, lung edema, adult respiratory distress syndrome, pain, and aggregation of platelets.