The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 1986
Filed:
May. 20, 1985
Applicant:
Inventors:
Norma G Delaney, Princeton, NJ (US);
Eric M Gordon, Pennington, NJ (US);
Assignee:
E. R. Squibb & Sons, Inc., Princeton, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; C07C / ; C07C / ; C07C / ; C07C / ; C07C / ; C07C / ; C07C / ; C07C / ; C07C / ; C07C / ; C07C / ; C07C / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
530332 ; 560 16 ; 560 34 ; 560 41 ; 560125 ; 560153 ; 560147 ; 560168 ; 560169 ; 562426 ; 562439 ; 562450 ; 562507 ; 562556 ; 562557 ; 562560 ; 562561 ;
Abstract
An enkephalin-degrading aminopentidase enzyme is inhibited by compounds having the formula ##STR1## and pharmaceutically acceptable salt thereof, wherein R.sub.1 and R.sub.2 are each independently hydrogen, alkyl, carboxyalkyl, halo substituted alkyl, hydroxyalkyl, aminoalkyl, mercaptoalkyl, alkylthioalkyl, (cycloalkyl)alkyl, (heteroaryl)alkyl, arylalkyl, carbamoylalkyl, guanidinylalkyl, or heteroaryl;