The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 15, 1986
Filed:
Feb. 15, 1983
Robert Auerbach, Middleton, WI (US);
Wisconsin Alumni Research Foundation, Madison, WI (US);
Abstract
A method for preparing a monoclonal antibody of improved cross-species specificity. The method includes the steps of preparing an inoculum antigen from a first species of animal producing the antigen and then immunizing a selected subject animal with the inoculum antigen. The method further includes the steps of fusing spleen cells from the immunized subject animal with myeloma cells to produce hybridomas. A test antigen is prepared corresponding to the inoculum antigen but derived from a second species of animal, distinct from the first species of animal from which the inoculum antigen was prepared. Hybridomas are screened for desired antibody production against the test antigen. The hybridoma producing antibodies most active against the test antigen is then cultured, and monoclonal antibodies are produced therefrom.