The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 1986
Filed:
Jul. 11, 1984
John G Parker, Olney, MD (US);
William D Stanbro, Columbia, MD (US);
The Johns Hopkins University, Baltimore, MD (US);
Abstract
A method and apparatus is disclosed for optically monitoring the concentration of singlet oxygen produced during photoradiation. A composite optical emission in the 1.27 micron frequency band is detected and electrically processed to separate a first component due to the decay of singlet oxygen from a second unwanted component due to the fluorescence of the photosensitizing dye. A chopped CW excitation source is used to excite the photosensitizing dye and a signal processing means such as a lock-in amplifier is used to separate the singlet oxygen emission component which appears out of phase from the chopped excitation signal and the in-phase photosensitizer fluorescence. The magnitude and/or other characteristics of the singlet oxygen emission component can be used to determine properties of complex biological or other media. In a therapeutic environment the magnitude and/or other characteristics of the singlet oxygen emission can be used by the treating physician to set a therapeutic light dosimetry.