The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 1986

Filed:

Nov. 21, 1983
Applicant:
Inventors:

Michael N Chang, Westfield, NJ (US);

Milton L Hammond, Edison, NJ (US);

Norman P Jensen, Princeton, NJ (US);

Robert A Zambias, Hoboken, NJ (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514459 ; 549 57 ; 514253 ; 549 60 ; 549355 ; 514309 ; 549408 ; 549462 ; 514310 ; 549510 ; 549511 ; 514312 ; 514313 ; 514361 ; 514362 ; 514363 ; 514367 ; 514369 ; 514370 ; 514382 ; 514383 ; 514414 ; 514422 ; 514443 ; 514444 ; 514469 ; 544405 ; 546143 ; 546160 ; 546269 ; 548126 ; 548128 ; 548151 ; 548159 ; 548193 ; 548256 ; 548266 ; 548454 ; 548525 ; 549 52 ;
Abstract

Substituted 5-hydroxy-2,3-dihydrobenzofuran and analogs such as the substituted 6-hydroxy-2,3-dihydrobenzopyrans were prepared from an appropriately substituted (5-hydroxy-2,3-dihydrobenzofuran-6-yl) formaldehyde or analog thereof with an aryl amine followed by reduction. These compounds were found to be potent topical anti-inflammatory agents.


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