The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 1985
Filed:
Mar. 27, 1985
Curt H Appelgren, Kungsbacka, SE;
Conny B Bogentoft, K.ang.llered, SE;
Gunnar H Ekenved, Kungsbacka, SE;
Aktiebolaget Hassle, , SE;
Abstract
According to the present invention an oral pharmaceutical preparation of acetylsalicylic acid is provided which consists of cores containing acetylsalicylic acid as pharmaceutically active component, which cores are coated with a polymer membrane to the formation of coated granules. The preparation is characterized in that the polymer membrane comprises at least one polymer selected from the group consisting of cellulose acetate phtalate and methyl esterified methacrylic acid polymers having a degree of esterification of 45-55%, whereby the amount of such polymer forms 60-45% of the weight of the membrane, and at least one methyl esterified methacrylic acid polymer having a degree of esterification of 65-75% and forming 45-25% of the weight of the membrane, and a plasticizer selected from fatty alcohols and fatty acids forming 4-12% of the weight of the membrane, whereby the membrane represents 5-12 weight % of the composition. With this composition a reduced effect on the gastric mucosa as compared with previously known preparations but retaining good absorbtion properties and a controlled release.