The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 1985

Filed:

Sep. 23, 1983
Applicant:
Inventors:

Masanori Fukushima, Nagoya, JP;

Osamu Hirai, Toyonaka, JP;

Toshitaka Manda, Osaka, JP;

Hiroyuki Kikuchi, Nishinomiya, JP;

Yasumasa Tsukitani, Sakuramura, JP;

Iwao Shimizu, Toyonaka, JP;

Yasuji Yamada, Hachioji, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; C07C / ; A61K / ;
U.S. Cl.
CPC ...
514530 ; 560121 ;
Abstract

Novel clavulone derivatives of the formula: ##STR1## wherein R.sup.1 and R.sup.2 combine together to form a keto group or either one of R.sup.1 and R.sup.2 is hydrogen atom and another one of them is hydroxy or acetoxy group, R.sup.3 and R.sup.4 are the same or different and are each hydrogen atom or acetoxy group, n is 0 or 1, provided that when the C--C bond between 8 and 12 positions is double bond, n is 0, a, b, c, d and e are each an integer of 1 or 2, and the dotted line means that the C--C bond is a single bond or double bond, or a salt thereof, which have excellent anti-inflammatory activity and anti-tumor activity and hence are useful as an anti-inflammatory agent or anti-tumor agent.


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