The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 1985
Filed:
Jun. 06, 1983
Applicant:
Inventor:
Christopher G Rudman, Thousand Oaks, CA (US);
Assignee:
Amgen, Thousand Oaks, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ;
U.S. Cl.
CPC ...
514-4 ; 514 14 ;
Abstract
Disclosed are novel methods and materials for developing hypoglycemic effects in mammals, including human. A pentadecapeptide ('deletion peptide') having the sequence, NH.sub.2 -Glu-Glu-Ala-Tyr-Ile-Pro-Lys-Glu-Gln-Lys-Tyr-Ser-Phe-Leu-Gln-COOH, is administered to the mammal contemporaneously with exogenous insulin to generate hypoglycemic effects greater than available through administration of insulin alone. The pentadecapeptide sequence is duplicative of the sequence of amino acid residues in human growth hormone in the region spanning positions thirty-two through forty-six.