The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 1985
Filed:
Mar. 10, 1983
Marianna Pongor nee Csakvari, Budapest, HU;
Gabor Nagy, Budapest, HU;
Gabor Horvath, Budapest, HU;
Maria David nee Kenez, Budapest, HU;
Sandor Bozsoky, Budapest, HU;
Sandor Virag, Budapest, HU;
Katalin Marmarosi nee Kellner, Biatorbagy, HU;
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt., Budapest, HU;
Abstract
The invention relates to synergistic antiphlogistic pharmaceutical compositions comprising a pyrido [1,2-a]-pyrimidine derivative of the Formula I ##STR1## wherein R.sup.1 and R.sup.2 are lower alkyl and R.sup.3 stands for lower alkoxycarbonyl or carbamoyl and the dotted line represents an optionally hydrogenated band or a salt or quaternary salt thereof and 1-[p-chloro-benzoly]-2-methyl-5-methoxy-indolyl-3-acetic acid of the Formula II ##STR2## The advantage of the compositions is that as a result of the synergistic activity of the compound of the Formula I, the antiphlogistic Indomethacin of the Formula II can be administered in a significantly lower doses and consequently the unfavorable side effects of the latter compound are mitigated.