The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 1985

Filed:

Aug. 03, 1984
Applicant:
Inventors:

David M Stout, Vernon Hills, IL (US);

Diane M Yamamoto, Gurnee, IL (US);

Cynthia Barcelon-Yang, Kenosha, WI (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; A61K / ;
U.S. Cl.
CPC ...
514336 ; 514340 ; 514341 ; 514348 ; 514349 ; 514350 ; 546278 ; 546275 ; 546283 ; 546284 ; 546288 ; 546296 ; 546297 ; 546298 ; 546299 ;
Abstract

Described are compounds of the formula ##STR1## wherein R is hydrogen, lower alkyl, halo, cyano, hydroxy, amino, lower alkylamino, --CH.sub.2 NH.sub.2, CH.sub.2 OH or COOR'; R' is hydrogen, lower cycloalkyl or lower alkyl; R' is lower alkyl or --CH.sub.2 Ar wherein Ar is phenyl, substituted phenyl, furan or thiophene; R'' is COOR', ##STR2## and x is oxygen or nitrogen; or a pharmaceutically acceptable salt thereof and their use in the treatment of impaired ventricular myocardial contractility. The compounds exhibit cardiotonic activity.


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