The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 1985
Filed:
Dec. 03, 1981
Applicant:
Inventors:
Assignee:
Takeda Chemical Industries, Ltd., Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; A61K / ;
U.S. Cl.
CPC ...
514210 ; 544359 ; 544360 ; 2602 / ; 544362 ; 544363 ; 2602454 ; 544364 ; 544365 ; 2603303 ; 544366 ; 544367 ; 2603309 ; 544369 ; 544370 ; 544 90 ; 544371 ; 544372 ; 544238 ; 544374 ; 544377 ; 544229 ; 544379 ; 544405 ; 544279 ; 544406 ; 544407 ; 544295 ; 544408 ; 544409 ; 544296 ; 546 14 ; 546114 ; 544298 ; 546122 ; 546123 ; 544300 ; 546153 ; 546155 ; 544301 ; 546156 ; 546157 ; 544310 ; 546159 ; 546162 ; 544311 ; 546187 ; 546193 ; 544316 ; 546194 ; 546197 ; 544317 ; 546208 ; 546209 ; 544319 ; 546210 ; 546211 ; 544320 ; 546256 ; 546261 ; 544321 ; 546263 ; 546264 ; 544322 ; 546270 ; 546275 ; 544323 ; 546276 ; 546277 ; 544324 ; 546278 ; 546279 ; 544325 ; 546280 ; 546281 ; 544327 ; 544331 ; 544332 ; 544333 ; 544334 ; 544335 ; 544336 ; 544357 ;
Abstract
Disclosed are compounds of the general formula: ##STR1## wherein R.sub.1 is amino, an acylated amino or a protected amino group, X is hydrogen or methoxy, and R' is hydrogen, R or R.sup.4 wherein R is an organic residue attached to the azetidine ring through a carbon atom therein and R.sub.4 is azido, a halogen, an amino group which may optionally be acylated or a group of the formula --OR.sub.5, ##STR2## or --S--S--R.sub.5 wherein R.sub.5 is an organic residue and n is 0, 1 or 2, and pharmaceutically acceptable salts and esters thereof. The compounds have antimicrobial and/or .beta.-lactamase-inhibitory activity and are of value as drugs for human beings and domesticated animals.