The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 1985
Filed:
May. 19, 1983
Applicant:
Inventors:
Hans Bruderer, Biel-Benken, CH;
Richard W Kierstead, North Caldwell, NJ (US);
John G Mullin, Jr, Hawthorne, NJ (US);
Keiji Nakamura, Kamakura, JP;
Mitsuru Tateishi, Atsugi, JP;
Teitel Sidney, Clifton, NJ (US);
Jay P O'Brien, Cedar Grove, NJ (US);
Assignee:
Hoffmann-La Roche Inc., Nutley, NJ (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ;
U.S. Cl.
CPC ...
514253 ; 514307 ; 544363 ; 544384 ; 544395 ; 546147 ; 546149 ;
Abstract
Substituted isoquinolines of the formula ##STR1## wherein R is lower alkoxy, n is the integer zero or 1, and A is ##STR2## wherein R.sub.1 is phenyl, halophenyl, lower-alkylphenyl or lower-alkoxyphenyl, and pharmaceutically acceptable acid addition salts thereof, are described. The compounds of formula I are useful in the treatment of cerebral and cardiac ischemias.