The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 1985
Filed:
Jul. 20, 1983
Applicant:
Inventors:
Oreste Piccolo, Leghorn, IT;
Aldo Belli, Cornate D'Adda, IT;
Giovanni Villa, Monticello, IT;
Enrico Zen, Macherio, IT;
Attilio Citterio, Monza, IT;
Assignee:
Biaschim S.p.A., Milan, IT;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C / ; C07C / ; C07C / ; C07C / ; C07C / ; C07C / ; C07C / ; C07C / ; C07C / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
560 21 ; 2604 / ; 2604 / ; 560-9 ; 560 17 ; 560 51 ; 560 52 ; 560 54 ; 560 59 ; 560 81 ; 560 82 ; 562431 ; 562435 ; 562460 ; 562463 ; 562469 ; 562488 ; 568 58 ; 568 63 ; 568 66 ; 568 68 ; 568306 ; 568312 ; 568315 ; 568316 ; 568424 ; 568433 ; 568585 ; 568586 ; 568631 ; 568635 ; 568636 ; 568637 ;
Abstract
Improvement in the process for preparing biaryl compounds via coupling of an arylamine with an arene in the presence of a nitrite, an acid and copper metal or a derivative thereof; the improvement is consisting in adding to the reaction mixture a trialkylorthoformate. The process may be used for preparing drugs such as Flurbiprofen and Xenbucin or intermediate compounds particularly useful for preparing Flurbiprofen, Flufenisal, Chlordimorin, Xenbucin, Xenysalate, Xenyhexenic acid and the like.