The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 30, 1985

Filed:

Jan. 20, 1984
Applicant:
Inventors:

Setsuro Fujii, Toyonaka, JP;

Toshiyuki Okutome, Tokyo, JP;

Toyoo Nakayama, Funabashi, JP;

Takashi Yaegashi, Funabashi, JP;

Masateru Kurumi, Narita, JP;

Assignee:

Torii & Co., Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; C07C / ; A61K / ;
U.S. Cl.
CPC ...
514466 ; 2604 / ; 560-9 ; 560 12 ; 560 19 ; 560 20 ; 560 34 ; 560 48 ; 560105 ; 560107 ; 514522 ; 514540 ; 549442 ;
Abstract

Amidino compounds represented by the formula ##STR1## and pharmaceutically acceptable acid addition salts thereof are novel compounds and are useful as powerful antitrypsine, antiplasmin, antikallikrein and antithrombin agents. Having strong anti-C1 (C1r, C1s) activities and an anticomplement activity, they are also useful as anticomplement agents. These amidino compounds are prepared by usual esterification of carboxylic acid compounds represented by the formula ##STR2## with 6-amidino-2-naphthol and, if necessary, can be transformed into pharmaceutically acceptable acid addition salts thereof.


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