The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 1985
Filed:
May. 21, 1984
Applicant:
Inventors:
Setsuro Fujii, Toyonaka, JP;
Takashi Yaegashi, Funabashi, JP;
Toyoo Nakayama, Funabashi, JP;
Yojiro Sakurai, Kamakura, JP;
Shigeki Nunomura, Chiba, JP;
Toshiyuki Okutome, Tokyo, JP;
Assignee:
Torii & Co. Ltd., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
549442 ; 560 35 ; 562440 ; 549436 ; 564247 ; 2604 / ; 560-1 ; 560-9 ; 560 12 ; 560 18 ; 560 20 ; 560 32 ; 560 34 ; 560 37 ; 560 48 ; 560 49 ; 560 51 ; 560 55 ; 560 66 ; 560 72 ; 560 75 ; 560 81 ; 560 86 ; 560104 ; 560105 ; 560107 ; 560109 ; 560115 ; 560122 ; 560123 ; 560124 ; 560125 ; 560128 ; 560140 ; 560142 ; 560 61 ;
Abstract
Amidino compounds represented by the formula (I) ##STR1## and pharmaceutically acceptable acid addition salts thereof are novel compounds and are useful as powerful antitrypsine, antiplasmin, antikallikrein and anti-thrombin agents. Having strong anti-Cl (Clr, Cls) activities and an anticomplement activity, they are also useful as anticomplement agents. These amidino compounds are prepared by usual esterification of carboxylic acid compounds represented by the formula (II)