The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 1985

Filed:

Mar. 30, 1982
Applicant:
Inventors:

Howard M Lenhoff, Costa Mesa, CA (US);

That T Ngo, Irvine, CA (US);

Assignee:

University of California, Berkeley, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ; C12N / ;
U.S. Cl.
CPC ...
435-7 ; 435188 ; 435810 ; 436515 ; 436529 ; 436535 ; 436536 ; 436537 ; 436538 ; 436539 ; 436540 ; 436541 ; 436542 ;
Abstract

A conjugate useful in determining the amount of antigen or antibody in a liquid sample, said conjugate having a marker, an immunoreactive component (i.e. antigen or antibody) bound to the marker and an insolubilizing binding component which is also bound to the marker. The insolubilizing binding component portion of the conjugate will react with an insolubilizing receptor to form a solid product of conjugate and receptor unless the conjugate reacts with the corresponding antigen or antibody to be analyzed in which event the conjugate will not react with the insolubilizing receptor. The conjugate will be added to a liquid sample containing an unknown amount of, for example, an antibody. A known amount of the corresponding antigen is also added which reacts with both the conjugate and antibody. After the reaction is complete, the liquid sample is contacted with the insolubilizing receptor. Since only the free conjugate reacts with the insolubilizing receptor the amount of antibody originally in the liquid sample can be determined by measuring the activity of the marker in the precipitate.


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