The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 05, 1985
Filed:
Jun. 18, 1984
Applicant:
Inventors:
William F Hoffman, Lansdale, PA (US);
Ta-Jyh Lee, Lansdale, PA (US);
Robert L Smith, Lansdale, PA (US);
Alvin K Willard, Wilmington, DE (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07C / ; C07C / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
424305 ; 2604299 ; 2604 / ; 2605011 ; 26050115 ; 514563 ; 514 63 ; 514459 ; 514538 ; 514539 ; 544358 ; 548327 ; 549292 ; 560 45 ; 560 49 ; 560116 ; 560119 ; 562455 ; 562498 ; 562501 ;
Abstract
Compounds of general structural formula: ##STR1## wherein Q is: ##STR2## or pharmaceutically acceptable salts, C.sub.1-3 alkyl esters or .alpha.-monoglyceride when Q is a dihydroxy acid are useful as antihypercholesterolemic agents for the treatment of atherosclerosis, familial hypercholesterolemia, hyperlipemia and like diseases. They also have useful antifungal activity.