The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 05, 1985
Filed:
May. 11, 1982
Applicant:
Inventors:
David R Brittain, Macclesfield, GB;
Robin Wood, Hazel Grove, GB;
Assignee:
Imperial Chemical Industries PLC, London, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514409 ; 546-8 ; 546 10 ; 546 18 ; 546 65 ; 546 81 ; 546153 ; 546165 ; 548302 ; 548404 ; 548410 ; 548411 ; 549 23 ; 549 24 ; 549 26 ; 549 27 ; 549 28 ; 549387 ; 549390 ; 549391 ; 549407 ; 549433 ;
Abstract
The invention provides various medical compositions for use in treating or preventing certain of the side effects of diabetes or galactosemia. The active ingredients are selected from a series of novel aldose reductase inhibitory spiro-linked pyrrolidine-2,5-diones of the general formula: ##STR1## or a pharmaceutically acceptable salt, or a non-toxic, biodegradable precursor thereof. Processes for the production of these compounds are also provided. A particular compound suitable for use as an active ingredient is spiro[pyrrolidine-3,9'-xanthene]-2,5-dione.