The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 1985
Filed:
Jul. 15, 1983
U James Lewis, La Jolla, CA (US);
The Whittier Institute for Diabetes and Endocrinology, La Jolla, CA (US);
Abstract
hGH(1-43) having the formula: H--Phe--Pro--Thr--Ile--Pro--Leu--Ser--Arg--Leu--Phe--Asp--Asn--Ala--Met--L eu--Arg--Ala--His--Arg--Leu--His--Gln--Leu--Ala--Phe--Asp--Thr--Try--Gln--G lu--Phe--Glu--Glu--Ala--Try--Ile--Pro--Lys--Glu--Gln--Lys--Tyr--Ser--OH has been found to have remarkable insulin-potentiating action, as has the fragment hGH (17-43). Pharmaceutical compositions in accordance with the invention include hGH(1-43), hGH(17-43) or a biologically active intermediate fragment, or a nontoxic salt thereof, dispersed in a pharmaceutically acceptable carrier. Such peptides or pharmaceutically acceptable salts thereof may be administered to mammals to promote the action of insulin. Such a peptide can be synthesized by exclusively solid-phase techniques, by partial solid-phase techniques, by fragment condensation, by classical solution addition or by recently developed recombinant DNA techniques.