The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 22, 1985

Filed:

Oct. 21, 1982
Applicant:
Inventors:

Robert T Buckler, Edwardsburg, MI (US);

Frederick E Ward, Elkhart, IN (US);

Assignee:

Miles Laboratories, Inc., Elkhart, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07G / ; C12N / ; G01N / ;
U.S. Cl.
CPC ...
435-7 ; 2601 / ; 2601 / ; 2601 / ; 260121 ; 424 85 ; 424 88 ; 435188 ; 436528 ; 436536 ; 544 47 ;
Abstract

Tricyclic antidepressant drug (e.g., imipramine, desipramine, amitriptyline, or nortriptyline) immunogens, antibodies prepared therefrom, labeled conjugates, synthetic intermediates, and the use of such antibodies and labeled conjugates in immunoassays for determining such drug. The immunogens comprise the drug coupled at its 2'-position to an immunogenic carrier material. Similarly, the labeled conjugates and synthetic intermediates are 2'-derivatives of the drug or a precursor thereof. The antibodies and labeled reagents are particularly useful in certain homogeneous nonradioisotopic immunoassays for measuring tricyclic antidepressant drugs in biological fluids such as serum.


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