The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 1984
Filed:
May. 11, 1983
Applicant:
Inventors:
Marcia I Dawson, Los Altos, CA (US);
Rebecca L Chan, Palo Alto, CA (US);
Assignee:
SRI International, Menlo Park, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; C07C / ; C07C / ; A61K / ;
U.S. Cl.
CPC ...
424312 ; 2604105 ; 2604106 ; 2604109 ; 260413 ; 260404 ; 424314 ; 424318 ; 424320 ; 424324 ; 2604 / ;
Abstract
Open ring retinoic acid analogues and 2Z isomers of the formula ##STR1## where X is ##STR2## and R is hydroxy, alkoxy with 0 or 1 hydroxy substituent, aroxy with 0 or 1 hydroxy or alkoxy-monosubstituted phenoxy or NR.sup.1 R.sup.2 where R.sup.1 is hydrogen, alkyl, or aryl and R.sup.2 is alkyl or aryl are disclosed. These retinoids are useful as chemopreventive agents for inhibiting tumor promotion in epithelial cells and for treating nonmalignant skin disorders.