The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 27, 1984
Filed:
Oct. 04, 1982
Applicant:
Inventors:
Michael Mezei, Halifax, CA;
Fredric J Nugent, Halifax, CA;
Assignee:
Lipoderm Pharmaceuticals Limited, Nova Scotia, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; B01J / ;
U.S. Cl.
CPC ...
264-46 ; 424 38 ; 424182 ; 424-11 ; 4284022 ; 436829 ;
Abstract
This invention provides an improved procedure for producing large multilamellar lipid vesicles (MLV), which may be used to encapsulate a biologically active material, particularly lipophilic substances. According to this invention, a lipid film is formed on inert, solid contact masses within a vessel, by evaporating an organic solvent therefrom. Subsequent agitation in the presence of an aqueous liquid, followed by a period in which the vessel remains undisturbed yields the multilamellar vesicles. The procedure permits the encapsulation of both hydrophilic and lipophilic materials.