The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 28, 1984

Filed:

Mar. 31, 1982
Applicant:
Inventors:

Yoshimasa Machida, Ibaraki, JP;

Isao Saito, Tokyo, JP;

Isao Sugiyama, Tokyo, JP;

Shigeto Negi, Tokyo, JP;

Seiichiro Nomoto, Tokyo, JP;

Hironori Ikuta, Tokyo, JP;

Hiroshi Yamauchi, Ibaraki, JP;

Kyosuke Kitoh, Saitama, JP;

Assignee:

Eisai Co., Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
424246 ; 2602391 ; 424256 ; 424258 ; 424271 ; 544 21 ; 544 25 ; 544 27 ; 544 28 ; 544 30 ;
Abstract

A compound represented by the formula: ##STR1## wherein R.sub.1 is hydrogen or methoxy; R.sub.2 is hydrogen or hydroxy; R is ##STR2## wherein R.sub.3 and R.sub.4 are hydroxy or acyloxy, Y is oxygen, sulfur or >N-R.sub.5 wherein R.sub.5 is hydrogen or lower alkyl, and Z is sulfur or >N-R.sub.5 wherein R.sub.5 has the same meanings as defined above; and X is ##STR3## wherein R.sub.6 is acyloxy or nitrogen-containing heterocyclicthio which may have substituent(s), a pharmaceutically accpetable salt thereof, and a carboxylic ester thereof. This compound has improved antibacterial activity against Kleb. pneumoniae and Pseud. aeruginosa.


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