The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 1984
Filed:
Jun. 10, 1982
Applicant:
Inventors:
Nancy M Lee, San Francisco, CA (US);
Horace H Loh, San Francisco, CA (US);
Jaw-Kang Chang, San Carlos, CA (US);
Assignee:
The Regents of the University of California, Berkeley, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; A61K / ;
U.S. Cl.
CPC ...
2601 / ; 424177 ;
Abstract
Dynorphin(1-13) has been previously reported to antagonize the analgesia induced by narcotics in naive hosts. Novel compounds are provided which differ from dynorphin(1-13) by neither potentiating nor antagonizing narcotics, such as morphine, in naive animals. In tolerant hosts the new compounds potentiate narcotic or peptide induced analgesia, and in addition are less susceptible to degradation than dynorphin(1-13). Particularly preferred of the new compounds are polypeptides having ten amino acids with nitrogen containing moieties at both termini.