The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 1984
Filed:
Jun. 18, 1982
Applicant:
Inventors:
Zoltan A Tokes, Los Angeles, CA (US);
Kathryn E Rogers, Pasadena, CA (US);
Alan Rembaum, Pasadena, CA (US);
Assignee:
University of Southern California, Los Angeles, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ;
U.S. Cl.
CPC ...
424-11 ; 424-9 ; 424 16 ; 424 31 ; 424 32 ; 424 78 ; 424 80 ; 424 81 ; 424 82 ; 424 83 ;
Abstract
Anthracycline cancer drugs are covalently coupled to polymeric particles having a diameter of greater than about 0.5 microns to produce pharmaceutical preparations having enhanced cytostatic activity. The coupling of drugs to polymeric carriers shows increased activity against cancer cells, allows the bound drug to retain its cytostatic activity after repeated uses and shows an increase in activity against drug resistant cells.