The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 03, 1984
Filed:
Aug. 19, 1983
Hiroshi Hayashi, Fuji, JP;
Masanobu Komiya, Nagaokakyo, JP;
Asahi Kasei Kogyo Kabushiki Kaisha, Osaka, JP;
Dainippon Pharmaceutical Co., Ltd., Osaka, JP;
Abstract
A method for stabilizing Tumor Necrosis Factor (TNF), which comprises adding a stabilizing agent selected from a nonionic surfactant, at least one substance selected from the group consisting of D-glucose, D-galactose, D-xylose, D-glucuronic acid, a salt of D-glucuronic acid, trehalose, a dextran and a hydroxyethyl starch, and mixtures thereof to an aqueous solution or powder containing TNF, and a stable aqueous solution or powder which contains TNF and an effective amount of such a stabilizing agent selected from a nonionic surfactant, a specific sugar or sugar-related compound and mixtures thereof. The aqueous solution or powder containing TNF can be stored for a prolonged period of time without losing its activity, and is stable on freezing, thawing, lyophilization, heat-treatment or the like.