The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 26, 1984

Filed:

Aug. 06, 1981
Applicant:
Inventors:

Yasuhiko Kojima, Yokohama, JP;

Seishi Konno, Tokyo, JP;

Takashi Hashimoto, Chofu, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
424195 ;
Abstract

An interferon inducer isolated from the plant tissue, having an elemental analysis of H: 6.54.+-.0.3% C: 41.9.+-.0.3%, N: 2.39.+-.0.3% and P: 0.28.+-.0.03% and a molecular weight of from about 100,000 to about 3,000,000 (mainly about 200,000 to about 1,000,000) and containing as main constituents amino acids, sugars and phosphoric acid. This substance is believed to be a homogeneous polymer of protein and sugars, containing phosphoric acid. This substance has an excellent interferon inducing activity and low toxicity and is significantly active against various viruses. The interferon inducer may be produced by extracting a substance having interferon inducing activity from the tissue of a plant of the genus Carthamus of the family Compositae or a variant thereof containing said active substance and recovering the active substance from the extract thereby obtained. Preferably, the active substance may be extracted from the flower of this plant with water and the recovery may be effected by ultrafiltration using a membrane capable of fractionating substances having a molecular weight of from 200,000 to 1,000,000. Pharmaceutical composition of this invention comprises as active ingredient the interferon inducer of this invention in association with a pharmaceutical carrier or excipient.


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